EMIT II Plus 6-Acetylmorphine Assay
Accurately screen for heroin use
EMIT II Plus 6-Acetylmorphine Assay Performance
| Assay Principle | Homogeneous Enzyme Multiplied Immonoassay (EMIT) |
| Cut-off | 10 ng/mL |
| Assay range | 0-20 ng/mL |
| Sample | Urine |
| Reagent Stability | Unopened until expiration date; Opened working reagent, 4 weeks |
| Calibration Frequency | Based on control results |
Qualitative Precision (mA/min)
| Level | Mean | Repeatability | Within-Lab | |||
| (ng/mL) | SD | %CV | SD | %CV | ||
| Control 1 | 7.5 ng/mL | 558 | 1.5 | 0.3 | 7 | 1.3 |
| Cut-off | 10.0 ng/mL | 591 | 1.7 | 0.3 | 6.5 | 1.1 |
| Control 2 | 12.5 ng/mL | 622 | 1.7 | 0.3 | 6 | 1 |
Semi-quantitative Precision (ng/mL)
| Level | Mean | Repeatability | Within-Lab | |||
| (ng/mL) | SD | %CV | SD | %CV | ||
| Control 1 | 7.5 ng/mL | 8.7 | 0.12 | 1.4 | 0.43 | 5.1 |
| Cut-off | 10.0 ng/mL | 11.3 | 0.14 | 1.5 | 0.48 | 4.2 |
| Control 2 | 12.5 ng/mL | 14.2 | 0.16 | 1.1 | 0.5 | 3.5 |
Assay Specificity
Concentrations of compounds that produce negative results vs. the 10 ng/mL cut-off
| Compounds Concentration Tested | (ng/mL) |
| Buprenorphine | 1,000,000 |
| Codeine | 500,000 |
| Dextromethorphan | 100,000 |
| Dihydrocodeine | 500,000 |
| Heroin | 80 |
| Hydrocodone | 300,000 |
| Hydromorphone | 100,000 |
| Imipramine | 200,000 |
| Levorphanol | 100,000 |
| Meperidine | 800,000 |
| Morphine | 100,000 |
| Morphine-3-Glucuronide | 600,000 |
| Morphine-6-Glucuronide | 600,000 |
| Nalorphine | 100,000 |
| Naloxone | 300,000 |
| Naltrexone | 300,000 |
| Norcodeine | 600,000 |
| Normophine | 100,000 |
| Oxycodoen | 400,000 |
| Oxymorphone | 100,000 |
Ordering information
| 9R129UL | EMIT® II Plus 6-Acetylmorphine Assay, large | R1=1000 mL and R2=500 mL |
| 9R039UL | EMIT II Plus 6-Acetylmorphine Assay, small | R1=28 mL and R2=14 mL |
| 9A509UL | EMIT Calibrator/Control Level 0 | 14 mL |
| 9R529UL | EMIT II Plus 6-AM/Ecstasy Calibrator/Control Level 1 | 10 mL |
| 9R549UL | EMIT II Plus 6-AM/Ecstasy Calibrator/Control Level 2 | 10 mL |
| 9R569UL | EMIT II Plus 6-AM/Ecstasy Calibrator/Control Level 3 | 10 mL |
| 9R589UL | EMIT II Plus 6-AM/Ecstasy Calibrator/Control Level 4 | 10 mL |